Makakatana Bay Lodge offers full day safaris exploring the wetlands and shorelines by boat, morning and evening game drives with sundowners, and spectacular bird watching. Within the iSimangaliso Wetland Park the animals found include: Elephant, Rhino, Buffalo, Leopard, Hyena, Wildebeest, Zebra, Giraffe, Hippo, Crocodile and many other types of antelope.

The lodge also offers deep sea fishing, fly fishing, whale watching, horse back safaris and diving at an additional cost.